It causes episodes of watery diarrhea and belly pain. Your large intestine is part of your digestive gastrointestinal or GI tract. It includes both the colon and rectum. It goes from your mouth all the way to your rectal opening. The large intestine receives the broken-down products of food from the small intestine. One of its main jobs is to reabsorb water and electrolytes, such as salt. The colon leads to the rectum, which stores your feces before your body expels them. In lymphocytic colitis, inflammatory cells from your immune system travel to your large intestine.
Here they cause swelling and inflammation of the tissues.
- Collagenous and Lymphocytic Colitis Symptoms.
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In rare cases, these cells also invade the latter part of the small intestine. Immune cells lymphocytes may build up in the area as well. The inflammation may keep your large intestine from reabsorbing as much water as it should. This leads to diarrhea, belly pain, and other symptoms. Lymphocytic colitis is one type of inflammatory bowel disease IBD.
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IBD is a group of conditions that cause inflammation in either the small or large intestine. Lymphocytic colitis is a type of microscopic colitis. Microscopic colitis is inflammation of the large intestine that can only be seen through a microscope. The other main type of microscopic colitis is collagenous colitis. Some experts think lymphocytic colitis and collagenous colitis might be the same illness presented in different ways.
What causes lymphocytic colitis?
Lymphocytic colitis is not common. But it can affect younger adults and children. Experts are trying to understand what causes the inflammation of the large intestine that leads to lymphocytic colitis. Some people think that something in the GI tract triggers this abnormal immune response. This might be bacteria, pollen, or food. Taking certain medicines may also trigger the condition in some people. These medicines can include:.
Certain bacteria may trigger lymphocytic colitis in some people. These can include Campylobacter jejuni or Clostridium difficile. Toxins in these bacteria may harm the inner surface of your large intestine.
This can cause inflammation. Some experts think certain viruses may also play a role in lymphocytic colitis. Some foods may bring on the condition in some people. Certain foods may also make lymphocytic colitis symptoms worse. These can include caffeine and milk products. Having certain health issues may increase your risk for the disease.
These include:. Being a smoker may increase your risk for the issue. Smoking interferes with the blood flow that your intestines need. Your risk for lymphocytic colitis may also be higher if someone in your family has the condition or another inflammatory bowel disease. The main symptom of lymphocytic colitis is watery diarrhea.
Dietrich CF. Lymphocytic and collagenous colitis microscopic colitis : Clinical manifestations, diagnosis, and management. Burke KE, et al. Identification of menopausal and reproductive risk factors for microscopic colitis—Results from the Nurses' Health Study. In press. Bonderup OK, et al. Alimentary Pharmacology and Therapeutics. Micromedex 2. Microscopic colitis adult.
Rochester, Minn. Camillari M, et al. Pathophysiology, evaluation, and management of chronic watery diarrhea. Gastroenterology ; Diarrhea nutrition therapy.
Microscopic colitis - Symptoms and causes - Mayo Clinic
Nutrition Care Manual. Academy of Nutrition and Dietetics. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Rajan E expert opinion. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Patients are commonly given an incorrect diagnosis of irritable bowel syndrome. Other diagnostic procedures include:.
Routine blood tests will be ordered to look for any abnormalities. Your doctor may also want to collect a stool sample for analysis. The endoscope or colonoscope is flexible and able to accommodate bends in the colon.
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A colonoscopy allows your doctor to see the largest area, including anus, rectum and colon. Avoiding aspirin for seven days prior to the procedure if a biopsy removing some tissue for analysis will be performed. This will minimize the risk of bleeding. Cleaning your colon using a bowel preparation.